Stevens M T
Toxicology. 1976 Mar;5(3):311-8. doi: 10.1016/0300-483x(76)90050-0.
It is accepted practice in presenting organ weight data to express the results relative to the animal's body weight. The data presented suggest that in rats no benefits are obtained from this method either in reducing the variability of the data or in removing bias due to different body weights. By using simulated data it is further shown that relative weights can lead to erroneous conclusions and misinterpretation of drug effects and it is concluded that workers should present their results in absolute as opposed to relative weights.
在呈现器官重量数据时,按动物体重来表达结果是公认的做法。所呈现的数据表明,对于大鼠而言,这种方法在降低数据变异性或消除因体重不同导致的偏差方面均无益处。通过使用模拟数据进一步表明,相对重量可能会导致错误结论以及对药物效果的误解,因此得出结论:研究人员应采用绝对重量而非相对重量来呈现结果。