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[淋巴结清扫范围对导管腺癌或壶腹周围胰腺癌胰头切除术后的发病率及预后有影响吗?]

[Does the extent of lymph node dissection have an effect on morbidity and prognosis after resection of the head of the pancreas for ductal or periampullary pancreatic carcinoma?].

作者信息

Böttger T, Boddin J, Küchle R, Junginger T

机构信息

Klinik und Poliklinik für Allgemein- und Abdominalchirurgie, Johannes-Gutenberg-Universität Mainz.

出版信息

Langenbecks Arch Chir. 1997;382(4):209-15.

PMID:9445967
Abstract

We examined the influence of lymph node dissection on morbidity and mortality of 13 patients after resection of the head of pancreas due to a ductal or periampullary carcinoma. In both groups the radicality of the operation was the main prognostic factor. In ductal pancreatic carcinoma the R-status was able to be determined better by normalisation of the postoperative Ca 19-9 serum level than by the evaluation of the surgeon or pathologist. For prognosis, the quotient of metastatic lymph nodes to resected lymph nodes indicates that an extensive lymph node dissection may increase the long term survival. A lymph node dissection is therefore to be recommended, especially since it does not increase the rate of postoperative complications.

摘要

我们研究了淋巴结清扫对13例因导管或壶腹周围癌行胰头切除术后患者发病率和死亡率的影响。在两组中,手术的根治性都是主要的预后因素。在导管腺癌中,术后血清Ca 19-9水平正常化比外科医生或病理学家的评估更能准确确定R状态。就预后而言,转移淋巴结与切除淋巴结的比值表明广泛的淋巴结清扫可能提高长期生存率。因此,建议进行淋巴结清扫,特别是因为它不会增加术后并发症的发生率。

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