Ozaki H, Kishi K
Jpn J Clin Oncol. 1983 Jun;13(2):371-7.
Resected specimens from 41 cases of carcinoma of the head of the pancreas or the periampullary region and autopsy specimens from 16 patients with recurrence were examined for lymph node metastasis. Evidence demonstrating the need for dissection and removal of specific lymph node groups in pancreatoduodenectomy or total pancreatectomy was discussed. These include the common hepatic and celiac groups, the superior mesenteric group, the jejunal group located in the mesentery of the proximal portion of the jejunum, and the retropancreatic group located behind the uncinate process. Metastasis to these groups was found even in cases where the carcinoma was considered small. In carcinoma of the head of the pancreas, metastasis to the peripancreatic lymph nodes was seen more widely. Therefore, total pancreatectomy with lymph node dissection is desirable for this disease.
对41例胰头或壶腹周围癌的切除标本以及16例复发患者的尸检标本进行了淋巴结转移检查。讨论了在胰十二指肠切除术或全胰切除术中进行特定淋巴结群清扫和切除的必要性证据。这些淋巴结群包括肝总动脉和腹腔动脉周围淋巴结群、肠系膜上淋巴结群、位于空肠近端系膜内的空肠淋巴结群以及位于钩突后方的胰后淋巴结群。即使在癌灶被认为较小的病例中,也发现了这些淋巴结群的转移。在胰头癌中,胰周淋巴结转移更为广泛。因此,对于这种疾病,行全胰切除术并进行淋巴结清扫是可取的。