Motta P M, Nottola S A, Makabe S
Department of Anatomy, University of Rome La Sapienza, Italy.
Eur J Obstet Gynecol Reprod Biol. 1997 Dec;75(1):5-10. doi: 10.1016/s0301-2115(97)00216-9.
This paper contains a number of sketches concerning the main morphological ultrastructural features of the human female germ cell during the prenatal period. The morphodynamic outline of primordial germ cells has been traced, both in their extraembryonic site of origin and during their migration towards the developing ovary. After gonadal settlement, the intraovarian differentiation of the germ cells into primary oocytes through the stage of oogonia, as well as the dramatic fall in the number of germ cells before birth, is described. The presence of morphofunctionally relevant interactions between the differentiating female gamete and the surrounding somatic microenvironment has also been evaluated and discussed.
本文包含了一些关于人类女性生殖细胞在产前阶段主要形态超微结构特征的草图。原始生殖细胞的形态动力学轮廓已被追踪，包括其在胚胎外起源部位以及向发育中的卵巢迁移过程中的情况。在性腺定植后，描述了生殖细胞在卵巢内通过卵原细胞阶段分化为初级卵母细胞的过程，以及出生前生殖细胞数量的急剧下降。还评估和讨论了分化中的雌配子与周围体细胞微环境之间存在的形态功能相关相互作用。
