van der Klei I J, Veenhuis M
Dept of Microbiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Haren, The Netherlands.
Trends Microbiol. 1997 Dec;5(12):502-9. doi: 10.1016/S0966-842X(97)01156-6.
Yeast peroxisomes harbour enzymes involved in the metabolism of specific growth substrates. Sequestration of these enzymes increases the efficiency of such pathways. Currently, 16 genes involved in peroxisome biogenesis have been identified, and analysis of their products suggests novel mechanisms for organelle assembly and protein translocation.
酵母过氧化物酶体含有参与特定生长底物代谢的酶。这些酶的隔离提高了此类代谢途径的效率。目前,已鉴定出16个参与过氧化物酶体生物发生的基因,对其产物的分析揭示了细胞器组装和蛋白质转运的新机制。