Wong K Y, Ngan K C, Sin V C, Lau W H
Radiotherapy and Oncology Department, Queen Elizabeth Hospital, Hong Kong.
Clin Oncol (R Coll Radiol). 1997;9(6):415-7. doi: 10.1016/s0936-6555(97)80144-6.
The long term complications of radiotherapy in treating patients with nasopharyngeal carcinoma (NPC) are well recognized. Among these, neurological and endocrinological complications are usually considered to be more clinically important. On the other hand, postirradiation sinusitis is often neglected or overlooked because symptoms are usually non-specific or not clinically disturbing. This leads to the under-reporting of this complication. We report the case history of a patient with NPC who developed recurrent and debilitating bouts of yawning attacks 13 years after radiotherapy. The attacks were thought to be due to the compression of the hypothalamus by a large mucocoele in the sphenoidal sinus, which was successfully managed by surgical drainage.
放射治疗鼻咽癌（NPC）患者的长期并发症已得到充分认识。其中，神经和内分泌并发症通常被认为在临床上更为重要。另一方面，放疗后鼻窦炎常常被忽视或忽略，因为症状通常不具有特异性或不会在临床上造成困扰。这导致该并发症的报告不足。我们报告了一例NPC患者的病史，该患者在放疗13年后出现反复发作且使人衰弱的打哈欠发作。这些发作被认为是由于蝶窦内一个大的黏液囊肿压迫下丘脑所致，通过手术引流成功治疗。
