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[两名鼻咽癌放疗后出现黏液囊肿]

[Post-radiation mucocele in two patients treated for nasopharyngeal cancer].

作者信息

Mnejja M, Hammami B, Achour I, Chakroun A, Charfeddine I, Frikha M, Daoud J, Ghorbel A

机构信息

Service ORL et chirurgie cervico-faciale, CHU Habib-Bourguiba, Sfax, Tunisie.

出版信息

Cancer Radiother. 2011 Jun;15(3):254-6. doi: 10.1016/j.canrad.2010.12.004. Epub 2011 Mar 17.

Abstract

A 30-year-old woman, with a history of nasopharyngeal carcinoma, which was treated by radiotherapy nine years previously, presented with occasional diplopia and recent headaches. A nasopharyngeal biopsy showed no recurrence. The imaging revealed a sphenoidal sinus mucocele. Endoscopic marsupialization of the mucocele allowed clinical improvement. A 56-year-old woman presented, five years after radiotherapy for nasopharyngeal carcinoma, with a fronto-orbital mass. CT-scan revealed a fronto-ethmoidal mucocele. Nasopharyngeal biopsy showed tumour recurrence. Marsupialization of mucocele was performed. Recurrence of the carcinoma was treated by radiotherapy and chemotherapy. Sphenoidal sinus mucocele developing after radiotherapy for nasopharyngeal carcinoma has rarely been reported. CT scan and MRI are useful tools in making the diagnosis. Biopsy is required to diagnose recurrence or associated radio-induced tumor. Endoscopic approach gives good results.

摘要

一名30岁女性,有鼻咽癌病史,9年前接受过放射治疗,现出现偶尔复视及近期头痛症状。鼻咽活检未发现复发。影像学检查显示蝶窦黏液囊肿。对黏液囊肿进行内镜下袋形缝合术使临床症状得到改善。一名56岁女性,在鼻咽癌放疗5年后出现额眶部肿块。CT扫描显示额筛窦黏液囊肿。鼻咽活检显示肿瘤复发。对黏液囊肿进行了袋形缝合术。对癌复发采用放疗和化疗进行治疗。鼻咽癌放疗后发生蝶窦黏液囊肿的情况鲜有报道。CT扫描和磁共振成像(MRI)是诊断的有用工具。需要活检来诊断复发或相关的放射性诱导肿瘤。内镜治疗方法效果良好。

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