Tomarev S I
Laboratory of Molecular and Developmental Biology, National Eye Institute, NIH, Bethesda, MD 20892-2730, USA.
Int J Dev Biol. 1997 Dec;41(6):835-42.
Eyes in different systematic groups including arthropods, molluscs and vertebrates probably have a common evolutionary origin. As a consequence of this, related genes are used for regulation of the early steps of eye development in different organisms. In this review, I briefly summarize data on three gene families which might be essential for eye development across species: Pax-6/eyeless, Eya/eyes absent and Prox/prospero with emphasis on our contribution here. Mechanisms of eye formation and the generation of different types of eyes in the course of evolution are discussed.
包括节肢动物、软体动物和脊椎动物在内的不同生物类群的眼睛可能有着共同的进化起源。因此，相关基因被用于调控不同生物体眼睛发育的早期阶段。在这篇综述中，我简要总结了关于三个可能对跨物种眼睛发育至关重要的基因家族的数据：Pax-6/无眼基因、Eya/无眼基因和Prox/原癌基因，并重点介绍了我们在此方面的贡献。文中还讨论了眼睛形成的机制以及进化过程中不同类型眼睛的产生。
