来自临床和食品分离株的气单胞菌属细菌的毒力因子与致病性的关系。

Virulence factors-pathogenicity relationships for Aeromonas species from clinical and food isolates.

作者信息

Pin C, Morales P, Marín M L, Selgas M D, García M L, Casas C

机构信息

Departamento de Nutrición y Bromatología III, Facultad de Veterinaria, Universidad Complutense, Madrid, Spain.

出版信息

Folia Microbiol (Praha). 1997;42(4):385-9. doi: 10.1007/BF02816954.

DOI:10.1007/BF02816954

PMID:9449784

Abstract

The presence of virulence factors in 96 Aeromonas strains isolated from food and clinical samples was studied. Neither cytotoxic activity and hydrophobicity, not the presence of pili or an extra surface layer made it possible to establish differences between food and clinical strains. Statistical studies showed that cytotoxin production was associated with a positive Voges-Proskauer reaction, inability to ferment arabinose and a positive lysine decarboxylation. Therefore, when comparing cytotoxic clinical and food strains with lysine decarboxylation phenotype, there was a significant difference (p < 0.05) between the two groups. The association of a cytotoxin production and lysine decarboxylation character should thus be considered as a possible virulence marker.

摘要

对从食品和临床样本中分离出的96株气单胞菌菌株中的毒力因子进行了研究。细胞毒性活性和疏水性，以及菌毛或额外表面层的存在，均无法使我们区分食品菌株和临床菌株。统计研究表明，细胞毒素的产生与Voges-Proskauer反应阳性、无法发酵阿拉伯糖以及赖氨酸脱羧反应阳性有关。因此，在比较具有赖氨酸脱羧表型的细胞毒性临床菌株和食品菌株时，两组之间存在显著差异（p < 0.05）。因此，细胞毒素产生与赖氨酸脱羧特性之间的关联应被视为一种可能的毒力标志物。