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雌激素对胎儿生长的调节作用。IV. 家兔生长加速胎儿的脑发育。

The regulatory effect of estrogens on fetal growth. IV. Brain development in growth accelerated fetuses in rabbits.

作者信息

Abdul-Karim R W, Pavy M, Beydoun S N, Haviland M E

出版信息

Biol Neonate. 1976;29(1-2):89-95. doi: 10.1159/000240852.

DOI:10.1159/000240852
PMID:945079
Abstract

Brain weights and DNA, RNA, and total protein concentrations were determined on 31-day-old fetuses whose growth had been accelerated incidental to estrogen deficiency following maternal oophorectomy. Compared to controls, there were no differences in the DNA, RNA, or total protein concentrations, although the mean brain weight was increased. The higher mean brain weight in the growth accelerated fetuses was related to the increased mean fetal weight, and did not represent an independent response to the estrogen deficiency. A comparison of the influence of fetal weight versus gestational age on the weight of the fetal brain shows that gestational age exerts an effect apart from that of fetal weight.

摘要

对31日龄胎儿的脑重量以及DNA、RNA和总蛋白浓度进行了测定,这些胎儿在母体卵巢切除术后因雌激素缺乏而生长加速。与对照组相比,DNA、RNA或总蛋白浓度没有差异,尽管平均脑重量增加了。生长加速胎儿较高的平均脑重量与胎儿平均体重增加有关,并不代表对雌激素缺乏的独立反应。比较胎儿体重与胎龄对胎儿脑重量的影响表明,胎龄除了对胎儿体重有影响外,还发挥着作用。

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