Heyman S N, Ginosar Y, Shapiro M, Kluger Y, Marx N, Maayan S
Department of Medicine, Hadassah University Hospital, Mount Scopus, Israel.
J Clin Gastroenterol. 1997 Dec;25(4):595-601. doi: 10.1097/00004836-199712000-00009.
We describe the clinical course and outcome of Rwandan refugees with cholera-like illness (n = 567) and clinical dysentery (n = 1,062) treated at the Israeli Army field hospital in the disaster region of Goma, Zaire, during the summer of 1994. Vigorous fluid administration was the primary therapy, complemented with antibiotics for patients with presumed Shigella infection. Recovery rates were 94% and 96% for patients with cholera and dysentery, respectively. Mortality was substantially affected by comorbid conditions such as pneumonia and meningitis, which occurred in one-quarter of these patients. Infective, metabolic, and surgical complications (including three cases of intussusception) may have contributed to the deaths. The outcome of patients during diarrheal epidemics of cholera or bacillary dysentery may be favorable, even in disaster settings, if patients are evacuated promptly to medical facilities and appropriate therapy is instituted. We close with general observations on procedures to be followed in future epidemics of diarrheal diseases.
我们描述了1994年夏天在扎伊尔戈马灾区的以色列军队野战医院接受治疗的患有霍乱样疾病(n = 567)和临床痢疾(n = 1,062)的卢旺达难民的临床病程及结果。积极补液是主要治疗方法,对于疑似志贺菌感染的患者辅以抗生素治疗。霍乱和痢疾患者的康复率分别为94%和96%。死亡率受到诸如肺炎和脑膜炎等合并症的显著影响,这些合并症在四分之一的患者中出现。感染性、代谢性和外科并发症(包括3例肠套叠)可能导致了死亡。如果患者能迅速被疏散到医疗设施并接受适当治疗,即使在灾难环境中,霍乱或细菌性痢疾腹泻流行期间患者的预后可能也是良好的。我们最后对未来腹泻病流行时应遵循的程序进行了总体观察。