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Apoptosis: a new pharmacodynamic endpoint.

作者信息

Au J L, Panchal N, Li D, Gan Y

机构信息

College of Pharmacy and Comprehensive Cancer Center, Ohio State University, Columbus 43210, USA.

出版信息

Pharm Res. 1997 Dec;14(12):1659-71. doi: 10.1023/a:1012159208559.

DOI:10.1023/a:1012159208559
PMID:9453051
Abstract
摘要

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本文引用的文献

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DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis.DFF是一种异二聚体蛋白，在细胞凋亡过程中，它在半胱天冬酶-3下游发挥作用，触发DNA片段化。
Cell. 1997 Apr 18;89(2):175-84. doi: 10.1016/s0092-8674(00)80197-x.
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Mechanisms of apoptotic cell death.凋亡性细胞死亡的机制。
Leukemia. 1997 Apr;11(4):457-65. doi: 10.1038/sj.leu.2400626.
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Controlling cell death.控制细胞死亡。
Mol Cancer Ther. 2014 Feb;13(2):275-84. doi: 10.1158/1535-7163.MCT-13-0791. Epub 2014 Jan 16.
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The investigation of a traditional Chinese medicine, Guizhi Fuling Wan (GFW) as an intravesical therapeutic agent for urothelial carcinoma of the bladder.桂枝茯苓丸（GFW）作为膀胱尿路上皮癌的膀胱内治疗药物的研究。
BMC Complement Altern Med. 2013 Feb 23;13:44. doi: 10.1186/1472-6882-13-44.
5
Evaluation of the anticancer potential of six herbs against a hepatoma cell line.评估六种草药对肝癌细胞系的抗癌潜力。
Chin Med. 2012 Jun 10;7(1):15. doi: 10.1186/1749-8546-7-15.
6
Modulation of tumor necrosis factor-mediated cell death by fullerenes.富勒烯对肿瘤坏死因子介导的细胞死亡的调节作用。
Pharm Res. 2008 Jun;25(6):1365-76. doi: 10.1007/s11095-007-9486-y.
7
Current concepts in apoptosis: the physiological suicide program revisited.细胞凋亡的当前概念：重新审视生理性自杀程序。
Cell Mol Biol Lett. 2006;11(4):506-25. doi: 10.2478/s11658-006-0041-3. Epub 2006 Sep 5.
8
Drug delivery and transport to solid tumors.药物向实体瘤的递送与转运。
Pharm Res. 2003 Sep;20(9):1337-50. doi: 10.1023/a:1025785505977.
9
Mdr1 transfection causes enhanced apoptosis by paclitaxel: an effect independent of drug efflux function of P-glycoprotein.多药耐药基因1（Mdr1）转染可增强紫杉醇诱导的细胞凋亡：这一效应独立于P-糖蛋白的药物外排功能。
Pharm Res. 2001 Jul;18(7):907-13. doi: 10.1023/a:1010919823936.
10
Differential response of the tail and body epidermis of Rana catesbeiana tadpoles in vitro to the anticancer drug, cisplatin.
In Vitro Cell Dev Biol Anim. 1999 Jan;35(1):8-11. doi: 10.1007/s11626-999-0035-3.
Science. 1997 Feb 21;275(5303):1081-2. doi: 10.1126/science.275.5303.1081.
4
TRAMP, a novel apoptosis-mediating receptor with sequence homology to tumor necrosis factor receptor 1 and Fas(Apo-1/CD95).TRAMP，一种与肿瘤坏死因子受体1和Fas（Apo-1/CD95）具有序列同源性的新型凋亡介导受体。
Immunity. 1997 Jan;6(1):79-88. doi: 10.1016/s1074-7613(00)80244-7.
5
Apoptosis and disease: regulation and clinical relevance of programmed cell death.细胞凋亡与疾病：程序性细胞死亡的调控及其临床意义
Annu Rev Med. 1997;48:267-81. doi: 10.1146/annurev.med.48.1.267.
6
CRADD, a novel human apoptotic adaptor molecule for caspase-2, and FasL/tumor necrosis factor receptor-interacting protein RIP.CRADD，一种新的半胱天冬酶-2的人类凋亡衔接分子，以及FasL/肿瘤坏死因子受体相互作用蛋白RIP。
Cancer Res. 1997 Feb 15;57(4):615-9.
7
Apoptosis by death factor.死亡因子介导的细胞凋亡
Cell. 1997 Feb 7;88(3):355-65. doi: 10.1016/s0092-8674(00)81874-7.
8
p53, the cellular gatekeeper for growth and division.p53，细胞生长和分裂的守门人。
Cell. 1997 Feb 7;88(3):323-31. doi: 10.1016/s0092-8674(00)81871-1.
9
The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis.细胞色素c从线粒体的释放：Bcl-2调控细胞凋亡的主要位点。
Science. 1997 Feb 21;275(5303):1132-6. doi: 10.1126/science.275.5303.1132.
10
Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked.Bcl-2对细胞凋亡的预防作用：线粒体中细胞色素c的释放受阻。
Science. 1997 Feb 21;275(5303):1129-32. doi: 10.1126/science.275.5303.1129.