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微创视频甲状旁腺切除术:犬类和人类的可行性研究

Minimally invasive videoscopic parathyroidectomy: a feasibility study in dogs and humans.

作者信息

Norman J, Albrink M H

机构信息

Department of Surgery, University of South Florida, Tampa 33612, USA.

出版信息

J Laparoendosc Adv Surg Tech A. 1997 Oct;7(5):301-6. doi: 10.1089/lap.1997.7.301.

DOI:10.1089/lap.1997.7.301
PMID:9453875
Abstract

BACKGROUND

With increasing experience using preoperative sestamibi nuclear scanning, several reports have shown that selective unilateral neck exploration is sufficient in most patients with primary hyperparathyroidism. The current study was undertaken to determine the feasibility of videoscopic parathyroidectomy as a means to decrease scar size while allowing adequate exposure for the identification of normal parathyroid glands and removal of those glands that are enlarged.

STUDY DESIGN

Eight mongrel dogs underwent removal of all parathyroid glands and both lobes of the thyroid using videoscopic techniques. Once the technical aspects of the operation were established, four patients with primary hyperparathyroidism underwent sestamibi-directed unilateral videoscopic neck exploration with attempted parathyroid removal.

RESULTS

All thyroid and parathyroid tissues were removed from each dog without complications. Maintenance of an adequate working space proved to be the major difficulty that necessitated placement of a small mechanical retractor. This problem was even more severe in humans, which prevented the identification of one of four adenomas and three of four normal glands.

CONCLUSIONS

Although videoscopic surgery is possible within the loose connective tissues of the canine neck, the inability to establish an adequate working space within the neck of humans and the location of parathyroid glands behind the thyroid precludes the use of this technique for patients with hyperparathyroidism.

摘要

背景

随着术前 sestamibi 核素扫描经验的增加,一些报告表明,对于大多数原发性甲状旁腺功能亢进患者,选择性单侧颈部探查就足够了。本研究旨在确定视频辅助甲状旁腺切除术的可行性,该手术可减小瘢痕大小,同时能充分暴露以识别正常甲状旁腺并切除肿大的甲状旁腺。

研究设计

八只杂种犬接受了视频辅助技术下的全甲状旁腺及双侧甲状腺叶切除。在确定手术技术要点后,四名原发性甲状旁腺功能亢进患者接受了 sestamibi 引导下的单侧视频辅助颈部探查并尝试切除甲状旁腺。

结果

每只犬的所有甲状腺和甲状旁腺组织均被切除,无并发症发生。维持足够的操作空间被证明是主要困难,这需要放置一个小型机械牵开器。在人体中这个问题更严重,导致无法识别四个腺瘤中的一个以及四个正常腺体中的三个。

结论

虽然在犬颈部的疏松结缔组织内进行视频辅助手术是可行的,但在人体颈部无法建立足够的操作空间以及甲状旁腺位于甲状腺后方,使得该技术无法用于甲状旁腺功能亢进患者。

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