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炎症性疾病的放射治疗——如今仍适用吗?(作者译)

[Radiotherapy of inflammatory diseases -- indicated still today? (author's transl)].

作者信息

Hassenstein E

出版信息

Med Klin. 1976 Jun 25;71(26):1117-9.

PMID:945444
Abstract

The good response of inflammatory diseases to a low dose radiotherapy is well known. Mainly, this fact is based on experiences made in the time before antibacterial chemotherapy area. In this study our results are presented which were obtained by treating 90 patients with radiotherapy in the last years, exlusively. With respect to the end of the treatment a success rate of more than 90% was achieved. This result was compared with literature and with own findings from radiotherapy of patients with degenerative joint diseases. From the viewpoint of radio-protection the radiotherapy should be initiated as early as possible because in these cases better results could be attained at low doses. Especially, the radiotherapy of the following diseases seems to be favourable: parotitis, mastitis, abscess, furuncle, paronychia and panaritium. Besides the complications and risks of the chemotherapy the somatic and genetic radiation injuries are discussed. When radiation therapy is applied skilfully the side effects of a locally and regionally limited therapy may be neglected. It is recommended to extend the indication for radiotherapy of inflammatory diseases.

摘要

炎症性疾病对低剂量放射治疗的良好反应是众所周知的。主要来说,这一事实基于抗菌化疗领域之前的经验。在本研究中,我们展示了过去几年仅通过放射治疗90例患者所获得的结果。关于治疗结束时,成功率超过了90%。该结果与文献以及退行性关节疾病患者放射治疗的自身研究结果进行了比较。从放射防护的角度来看,放射治疗应尽早开始,因为在这些情况下,低剂量时可获得更好的效果。特别是,以下疾病的放射治疗似乎效果良好:腮腺炎、乳腺炎、脓肿、疖、甲沟炎和脓性指头炎。除了化疗的并发症和风险外,还讨论了躯体和遗传辐射损伤。当放射治疗应用得当时,局部和区域受限治疗的副作用可能可以忽略不计。建议扩大炎症性疾病放射治疗的适应症。

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