Valvano L, Tassetti V, Vix M, Hirezi F, Sanchez-Guerra F, Marescaux J
Istituto di Chirurgia d'Urgenza, Digestiva ed Endocrina dell'Ospedale Universitario di Strasburgo, Francia.
Ann Ital Chir. 1997 May-Jun;68(3):315-9; discussion 319-20.
The purpose of this study is to evaluate the sequential endoscopic-laparoscopic approach for clearance of common bile duct (CBD) and removal of gallbladder in patients with simultaneous cholecystolithiasis and choledocholithiasis. A data base of 990 patients undergoing Laparoscopic Cholecystectomy (LC) was compiled during an 5 years period. 88 patients were suspected of having CBD stones based upon clinical, biological and ultrasound evidence. The CBD cannulation rate was 93% (82/88). CBD stones were found in 43 patients (49%). The stones were removed preoperatively by Endoscopic Sphincterotomy (ES) in 37 patients of these 43 cases (86%). LC was performed in all patients after endoscopic retrograde cholangiopancreatography (ERCP). This treatment had showed no mortality and a morbidity of 14%. Efficacy of this sequential method of treatment of LVBP was 86%. With inclusion of laparoscopic extractions, the efficacy rate was 91%. The rate of residual stones was 1% (1/88). Experience with ERCP and ES before LC has been growing. ERCP-SE in the treatment of choice to clear the CBD before LC in high risk elderly patients (26) as well as in complicated stones. However, in this era of laparoscopic surgery, CBD stone can be removed laparoscopically in specialized centres with the advantage of a non-invasive single procedure for the patient. Laparoscopic CBD desobstruction and ES are not opposite but complementary. Preoperative ERCP and ES should be reserved for patients with serious illness. All other patients should be managed laparoscopically; in this case the future of sequential treatment resides in a one step-approach: preoperative ERCP if cholangiography is positive.
本研究的目的是评估序贯性内镜-腹腔镜方法在同时患有胆囊结石和胆总管结石的患者中清除胆总管(CBD)及切除胆囊的效果。在5年期间收集了990例行腹腔镜胆囊切除术(LC)患者的数据库。基于临床、生物学和超声证据,88例患者被怀疑患有胆总管结石。胆总管插管率为93%(82/88)。43例患者(49%)发现胆总管结石。在这43例患者中的37例(86%)术前通过内镜括约肌切开术(ES)取出结石。所有患者在进行内镜逆行胰胆管造影(ERCP)后均行LC。该治疗无死亡病例,发病率为14%。这种序贯治疗方法治疗左心室后负荷增加的疗效为86%。加上腹腔镜取石,有效率为91%。残余结石率为1%(1/88)。在LC前进行ERCP和ES的经验不断增加。ERCP-SE是在高危老年患者(26例)以及复杂结石患者中在LC前清除CBD的首选治疗方法。然而,在这个腹腔镜手术时代,在专业中心可以通过腹腔镜取出胆总管结石,对患者来说具有单一非侵入性手术的优势。腹腔镜胆总管疏通术和ES并非相互对立而是互补的。术前ERCP和ES应保留给病情严重的患者。所有其他患者应采用腹腔镜治疗;在这种情况下,序贯治疗的未来在于一步法:如果胆管造影阳性则进行术前ERCP。