Linden H, Ballario P, Macino G
Dipartimento di Biopatologia Umana, Sezione Biologia Cellulare, Università di Roma "La Sapienza,", Viale Regina Elena, 324, Roma, 00161, Italy.
Fungal Genet Biol. 1997 Dec;22(3):141-50. doi: 10.1006/fgbi.1997.1013.
The fungus Neurospora crassa has been shown to be a paradigm for photobiological, biochemical, and genetic studies of blue light perception and signal transduction. Several different developmental and morphological processes of Neurospora are regulated by blue light and can be divided into early and late blue light responses. The characterization of two central regulator proteins of blue light signal transduction in Neurospora crassa, WC1 and WC2, and the isolation of light-regulated genes, indicate transcriptional control as a central step in blue light signalling.
粗糙脉孢菌已被证明是蓝光感知和信号转导的光生物学、生物化学及遗传学研究的典范。粗糙脉孢菌的几种不同发育和形态过程受蓝光调控,可分为早期和晚期蓝光反应。粗糙脉孢菌中蓝光信号转导的两种核心调节蛋白WC1和WC2的特性,以及光调控基因的分离,表明转录控制是蓝光信号传导的核心步骤。