Ortega-Larrocea G, Feregrino-Goyos M
Uveitis Department, Asociación para Evitar la Ceguera en México, México, D.F.
Ocul Immunol Inflamm. 1997 Dec;5(4):279-82. doi: 10.3109/09273949709085069.
Cytomegalovirus (CMV) retinitis is the most common opportunistic viral infection in acquired immunodeficiency syndrome (AIDS) patients with a low CD4+ count. Without specific treatment, the disease is an important cause of blindness. We report two cases of AIDS with nonprogressive CMV retinitis after undergoing a combined antiHIV treatment schedule including at least one protease inhibitor. The treatment was associated with an increase in circulating CD4+ lymphocytes. This newly available antiviral combination may well prevent the recurrence of CMV disease and decrease the morbidity of CMV retinitis.
巨细胞病毒(CMV)视网膜炎是获得性免疫缺陷综合征(AIDS)患者中最常见的机会性病毒感染,这些患者的CD4 +细胞计数较低。若不进行特异性治疗,该疾病是失明的重要原因。我们报告了两例AIDS患者,在接受包括至少一种蛋白酶抑制剂的联合抗HIV治疗方案后,患有非进行性CMV视网膜炎。该治疗与循环CD4 +淋巴细胞增加有关。这种新可用的抗病毒联合疗法很可能预防CMV疾病的复发并降低CMV视网膜炎的发病率。