通过DNA探针法检测的六种牙周病原体在HIV相关性牙周炎与非HIV相关性牙周炎中的患病率。
Prevalence of six periodontal pathogens detected by DNA probe method in HIV vs non-HIV periodontitis.
作者信息
Tenenbaum H, Elkaim R, Cuisinier F, Dahan M, Zamanian P, Lang J M
机构信息
Department of Periodontology, Dental Faculty, University Louis Pasteur, Strasbourg, France.
出版信息
Oral Dis. 1997 May;3 Suppl 1:S153-5. doi: 10.1111/j.1601-0825.1997.tb00350.x.
OBJECTIVE
The aim of the study was to examine the prevalence of selected periodontal pathogens associated with HIV and non-HIV related periodontal lesions.
METHODS
Subgingival plaque samples were obtained from both HIV-seropositive and HIV-seronegative patients affected with periodontal disease. DNA probes were used to detect Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia, Bacteroides forsythus, Eikenella corrodens and Campylobacter rectus.
RESULTS
A actinomycetemcomitans, P. intermedia and B. forsythus (P < 0.05) were more prevalent in HIV-seronegative patients with rapidly progressive periodontitis. Only C. rectus was slightly more prevalent in HIV-seropositive subjects with periodontal diseases, but this was not significant.
目的
本研究旨在调查与HIV相关和非HIV相关牙周病变有关的特定牙周病原体的患病率。
方法
从患有牙周疾病的HIV血清阳性和HIV血清阴性患者中获取龈下菌斑样本。使用DNA探针检测伴放线放线杆菌、牙龈卟啉单胞菌、中间普氏菌、福赛坦氏菌、具核梭杆菌和直肠弯曲菌。
结果
伴放线放线杆菌、中间普氏菌和福赛坦氏菌（P<0.05）在患有快速进展性牙周炎的HIV血清阴性患者中更为普遍。仅直肠弯曲菌在患有牙周疾病的HIV血清阳性受试者中略为普遍，但不显著。
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