Yano-Higuchi K, Takamatsu N, He T, Umeda M, Ishikawa I
Periodontology, Department of Hard Tissue Engineering, Graduate School, Tokyo Medical and Dental University, Japan.
J Clin Periodontol. 2000 Aug;27(8):597-602. doi: 10.1034/j.1600-051x.2000.027008597.x.
BACKGROUND, AIMS: This study investigated the prevalence of Bacteroides forsythus, Porphyromonas gingivalis and Actinobacillus actinomycetemcomitans among various periodontitis patients and healthy individuals in Japan, and correlated it with clinical parameters.
Subgingival plaque samples were collected from 21 patients with adult periodontitis (AP), 8 with rapidly progressive periodontitis (RPP) and 15 healthy individuals.
The frequency detected in culture was as follows: B. forsythus was found in 47.6% of AP sites and in 37.5% of RPP sites. P. gingivalis was identified in 64.3% of AP and 59.4% of RPP sites. A. actinomycetemcomitans was detected in 4.8% of AP and 3.1% of RPP sites. The 3 species were detected in only 2 of the healthy individuals. The proportion of B. forsythus in the total microflora in culture was 0.07% in the healthy group, 4.1% in AP and 2.4% in RPP. The proportions of P. gingivalis were 0% in the healthy group, 18.8% in AP and 16.2% in RPP. The proportion of A. actinomycetemcomitans was very low in all 3 groups. A DNA probe detected B. forsythus in 78.6% of AP and 65.6% of RPP sites, as well as P.gingivalis in 58.3% of AP and 59.4% of RPP sites. A. actinomycetemcomitans was detected in only 1.2% of AP sites. The 3 species were undetectable in the healthy group.
The prevalence and the proportion of B. forsythus and P. gingivalis were significantly correlated with clinical parameters, suggesting that B. forsythus and P. gingivalis are closely related to AP and RPP in the Japanese population.
本研究调查了日本各类牙周炎患者及健康个体中福赛斯坦纳菌、牙龈卟啉单胞菌和伴放线放线杆菌的患病率，并将其与临床参数相关联。
从21例成人牙周炎（AP）患者、8例快速进展性牙周炎（RPP）患者和15名健康个体中采集龈下菌斑样本。
培养检测到的频率如下：福赛斯坦纳菌在47.6%的AP位点和37.5%的RPP位点被发现。牙龈卟啉单胞菌在64.3%的AP位点和59.4%的RPP位点被鉴定出。伴放线放线杆菌在4.8%的AP位点和3.1%的RPP位点被检测到。这三种菌仅在2名健康个体中被检测到。培养中福赛斯坦纳菌在健康组总微生物群中的比例为0.07%，在AP组为4.1%，在RPP组为2.4%。牙龈卟啉单胞菌在健康组中的比例为0%，在AP组为18.8%，在RPP组为16.2%。伴放线放线杆菌在所有三组中的比例都非常低。一种DNA探针在78.6%的AP位点和65.6%的RPP位点检测到福赛斯坦纳菌，在58.3%的AP位点和59.4%的RPP位点检测到牙龈卟啉单胞菌。伴放线放线杆菌仅在1.2%的AP位点被检测到。在健康组中未检测到这三种菌。
福赛斯坦纳菌和牙龈卟啉单胞菌的患病率及比例与临床参数显著相关，表明在日本人群中，福赛斯坦纳菌和牙龈卟啉单胞菌与AP和RPP密切相关。
