Laiho K
Int J Legal Med. 1998;111(1):10-2. doi: 10.1007/s004140050102.
The measurement of myeloperoxidase activity was used to quantify the acute granulocyte reaction. Ethyl alcohol given intraperitoneally in rats as doses of 3, 4 and 5 g per kg body weight resulted in a clear decrease of the myeloperoxidase activity at the edges of incision wounds. When one-half of the LD 50 dose of chlorpromazine was given intraperitoneally a remarkable decrease in the myeloperoxidase activity was observed. Moderate decreases were obtained with one-half of the LD 50 dose of acetyl salisylic acid and Na-pentobarbital and with high therapeutic doses of hydrocortisone and indomethacin.
髓过氧化物酶活性的测定用于量化急性粒细胞反应。给大鼠腹腔注射剂量为每千克体重3、4和5克的乙醇，导致切口伤口边缘的髓过氧化物酶活性明显降低。当腹腔注射氯丙嗪半数致死剂量的一半时，观察到髓过氧化物酶活性显著降低。给予乙酰水杨酸和戊巴比妥钠半数致死剂量的一半以及氢化可的松和吲哚美辛的高治疗剂量时，髓过氧化物酶活性出现中度降低。
