Goldberg-Stern H, deGrauw T, Passo M, Ball W S
Department of Neurology, Children's Hospital Medical Center, Cincinnati 45229-3039, USA.
Neuroradiology. 1997 Dec;39(12):873-6. doi: 10.1007/s002340050525.
Parry-Romberg syndrome is a poorly--understood disorder characterized by progressive hemifacial atrophy involving the skin, soft tissue, and bone. Involvement of the central nervous system with impairment in neurologic function occurs infrequently. We describe a child with this syndrome in whom central nervous system involvement, documented on serial MRI, played a prominent role. We have attempted to correlate the clinical course with the radiologic findings, and to determine the impact of prednisone and methotrexate on the intracranial lesions.
帕里 - 龙贝格综合征是一种了解甚少的疾病，其特征为进行性半侧面部萎缩，累及皮肤、软组织和骨骼。中枢神经系统受累并伴有神经功能损害的情况很少见。我们描述了一名患有该综合征的儿童，其经系列磁共振成像（MRI）记录的中枢神经系统受累情况起到了显著作用。我们试图将临床病程与影像学表现相关联，并确定泼尼松和甲氨蝶呤对颅内病变的影响。
