Zakkiriah Mohammed, Al Khalaf Maryam Kh, Al Mutairi Muna A, Al Enezi Sarah
Department of Neurology, Al Adan Hospital, Ministry of Health, Hadiya, Kuwait. E-mail.
Saudi Med J. 2019 Jul;40(7):721-726. doi: 10.15537/smj.2019.7.24327.
Parry-Romberg syndrome is a rare disorder with progressive hemifacial atrophy of unknown etiology. We reported 2 cases of progressive hemifacial atrophy with different neurological manifestations from Kuwait. The first case was a 14-year-old boy who initially presented with recurrent transient stroke-like episodes followed by focal seizures and hemifacial atrophy. Magnetic resonance imaging showed significant white matter changes and cerebral hemiatrophy. The second case was a 7-year-old girl who presented with complex partial seizures and hemifacial atrophy, her magnetic resonance imaging scan showed minimal changes in the hemiatrophy of the temporal cerebral lobe. Both patients' disease activity was well controlled with immunosuppressive therapy and anticonvulsants. Parry-Romberg syndrome should be considered in any child with unexplained neurological symptoms.
帕里-罗姆伯格综合征是一种病因不明的罕见疾病，表现为进行性半侧面部萎缩。我们报告了2例来自科威特的具有不同神经学表现的进行性半侧面部萎缩病例。第一例是一名14岁男孩，最初表现为反复发作的短暂性中风样发作，随后出现局灶性癫痫发作和半侧面部萎缩。磁共振成像显示有明显的白质改变和大脑半球萎缩。第二例是一名7岁女孩，表现为复杂部分性癫痫发作和半侧面部萎缩，她的磁共振成像扫描显示颞叶脑叶半侧萎缩的变化极小。两名患者的疾病活动均通过免疫抑制治疗和抗惊厥药得到了良好控制。对于任何有不明原因神经症状的儿童，都应考虑帕里-罗姆伯格综合征。
