母体血清肌酸激酶作为输卵管妊娠的生化标志物。
Maternal serum creatine kinase as a biochemical marker of tubal pregnancy.
作者信息
Chandra L, Jain A
机构信息
Department of Biochemistry, Lady Hardinge Medical College and Smt. S.K. Hospital, New Delhi, India.
出版信息
Int J Gynaecol Obstet. 1995 Apr;49(1):21-3. doi: 10.1016/0020-7292(95)02340-i.
OBJECTIVE
To evaluate the role of serum creatine kinase as a possible marker for diagnosis of tubal pregnancy.
METHODS
Five groups of patients were included in this prospective study: group A, 20 patients with tubal pregnancies; group B, 20 patients with missed abortions; group C, 20 patients with pelvic inflammatory disease; group D, 10 patients with acute appendicitis; group E (controls), 20 patients with normal pregnancies matched for age and gestation. Total creatine kinase levels were measured in the serum of all five groups.
RESULTS
Creatine kinase levels were found to be > or =75 IU/l in all patients with tubal pregnancies, which was significantly higher than in the other four groups (P < 0.0001).
CONCLUSION
Our results indicate that maternal serum creatine kinase can be an important biochemical marker in suspected tubal pregnancy.
目的
评估血清肌酸激酶作为输卵管妊娠诊断潜在标志物的作用。
方法
本前瞻性研究纳入五组患者：A组，20例输卵管妊娠患者；B组，20例稽留流产患者；C组，20例盆腔炎患者；D组，10例急性阑尾炎患者；E组（对照组），20例年龄和孕周匹配的正常妊娠患者。检测所有五组患者血清中的总肌酸激酶水平。
结果
所有输卵管妊娠患者的肌酸激酶水平均≥75 IU/l，显著高于其他四组（P < 0.0001）。
结论
我们的结果表明，孕妇血清肌酸激酶可能是疑似输卵管妊娠的一项重要生化标志物。
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