肌酸激酶在异位妊娠诊断中的临床价值

Clinical value of creatinine kinase in the diagnosis of ectopic pregnancy.

作者信息

Vitoratos N, Gregoriou O, Papadias C, Konidaris S, Kalogirou D, Kalampokis D, Chryssikopoulos A

机构信息

2nd Department of Obstetrics and Gynecology, University of Athens, Areteion Hospital, Athens, Greece.

出版信息

Gynecol Obstet Invest. 1998 Aug;46(2):80-3. doi: 10.1159/000010006.

DOI:10.1159/000010006

PMID:9701684

Abstract

The role of creatinine kinase (CK) in the diagnosis of ectopic pregnancy was studied. We selected 56 patients divided into 4 groups. Group A consisted of 10 patients with asymptomatic tubal pregnancy, group B consisted of 11 patients with symptomatic tubal pregnancy whereas groups C and D consisted of 20 and 15 patients with normal and threatened intrauterine pregnancy, respectively. Serum samples of CK were taken from all patients on admission. No significant difference was observed in the median CK value of cases with normal pregnancy (58.5 +/- 7.24 U/1, mean +/- SE) as well as threatened abortion (73 +/- 11.43 U/1) compared to that of cases with asymptomatic 58.5 +/- 12.42 U/1) or symptomatic tubal pregnancy (59 +/- 10.08 U/1). We conclude that serum CK is not a useful biochemical marker in the diagnosis of ectopic pregnancy.

摘要

研究了肌酸激酶（CK）在异位妊娠诊断中的作用。我们选取了56例患者，分为4组。A组由10例无症状输卵管妊娠患者组成，B组由11例有症状输卵管妊娠患者组成，而C组和D组分别由20例正常宫内妊娠患者和15例先兆流产患者组成。所有患者入院时均采集CK血清样本。与无症状输卵管妊娠（58.5±12.42 U/1）或有症状输卵管妊娠（59±10.08 U/1）的患者相比，正常妊娠（58.5±7.24 U/1）以及先兆流产（73±11.43 U/1）患者的CK中位数无显著差异。我们得出结论，血清CK在异位妊娠诊断中不是一个有用的生化标志物。