孕妇血清肌酸激酶不能预测输卵管妊娠。
Maternal serum creatine kinase does not predict tubal pregnancy.
作者信息
Lincoln S R, Dockery J R, Long C A, Rock W A, Cowan B D
机构信息
Department of Obstetrics and Gynecology, University of Mississippi Medical Center, Jackson, USA.
出版信息
J Assist Reprod Genet. 1996 Oct;13(9):702-4. doi: 10.1007/BF02066421.
PURPOSE
Our purpose was to validate prospectively the predictive value of maternal serum creatine kinase in the evaluation of ectopic pregnancy.
METHODS
Fifty-one consecutive pregnant first-trimester patients who presented for suspected abnormal pregnancy were enrolled. Maternal serum samples were obtained and assayed for creatine kinase. Patients were subsequently evaluated for abnormal pregnancy by serial quantitative hCG levels, transvaginal ultrasonography, and surgery when appropriate. A receiver operating characteristic (ROC) curve was generated comparing intrauterine to extrauterine (ectopic) pregnancy.
RESULTS
Of 51 patients, 18 had an ectopic pregnancy, 16 had a spontaneous abortion, and 17 had an ongoing intrauterine pregnancy. The ROC curve revealed that maternal serum creatine kinase had no ability to predict ectopic pregnancy.
CONCLUSIONS
Maternal serum creatine kinase is not a reliable predictor of tubal pregnancy.
目的
我们的目的是前瞻性地验证母体血清肌酸激酶在异位妊娠评估中的预测价值。
方法
纳入51例连续就诊的孕早期疑似异常妊娠患者。采集母体血清样本并检测肌酸激酶。随后通过连续定量hCG水平、经阴道超声检查，并在适当情况下进行手术，对患者的异常妊娠情况进行评估。生成了一条比较宫内妊娠与宫外（异位）妊娠的受试者工作特征（ROC）曲线。
结果
51例患者中，18例为异位妊娠，16例为自然流产，17例为持续宫内妊娠。ROC曲线显示母体血清肌酸激酶无法预测异位妊娠。
结论
母体血清肌酸激酶不是输卵管妊娠的可靠预测指标。
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