Medves J M, O'Brien B A
Faculty of Nursing, University of Alberta, Edmonton.
Can J Public Health. 1997 Nov-Dec;88(6):380-2. doi: 10.1007/BF03403910.
The efficacy of alcohol or water in promoting umbilical cord separation was compared in a randomized controlled trial. Rates of skin colonization between groups were also evaluated on three occasions. Time to cord separation, rates of colonization, and species of organisms that colonized were compared between groups. Of 148 participants, 136 (92%) completed the protocol. Cords that were cleaned with sterile water separated more quickly than those cleaned with alcohol (t = 3.15, p = 0.002). Between-group differences in colonization rates were not found (F = 1.59, df = 2, p = 0.205). Umbilical or other infections did not occur. Bacterial colonization of the umbilical area and surrounding skin occurs over time in healthy term neonates. Cleaning with alcohol will increase the length of time from birth to cord separation but will not prevent colonization of the umbilical area.
在一项随机对照试验中，比较了酒精或水在促进脐带脱落方面的效果。还在三个时间点评估了两组之间的皮肤定植率。比较了两组之间脐带脱落的时间、定植率以及定植的生物体种类。在148名参与者中，136名（92%）完成了该方案。用无菌水清洁的脐带比用酒精清洁的脐带脱落得更快（t = 3.15，p = 0.002）。未发现两组之间定植率存在差异（F = 1.59，自由度 = 2，p = 0.205）。未发生脐带或其他感染。健康足月儿脐带区域和周围皮肤的细菌定植会随着时间的推移而发生。用酒精清洁会延长从出生到脐带脱落的时间，但不会防止脐带区域的定植。
