Dassori A M, Miller A L, Velligan D, Saldana D, Diamond P, Mahurin R
University of Texas, Health Science Center at San Antonio 78284-7792, USA.
Cult Divers Ment Health. 1998;4(1):65-9.
The purpose of this study was to assess ethnic differences in the negative symptom profile of 25 Anglo American and 26 Mexican American subjects with schizophrenia. Subjects were rated at the end of a 1-2-week medication washout period (time 1) and at discharge (time 2) with the Negative Symptoms Assessment (NSA), Brief Psychiatric Research Scale, (BPRS), the [Diagnostic and Statistical Manual of Mental Disorders (4th edition)] DSM-IV negative factor score and LAECA acculturation scale. Total NSA scores were significantly higher among Mexican Americans both at time 1 and time 2. Among the five subscales of the NSA, ethnic differences were significant only for the Cognition subscale at time 1. Results indicate no ethnic differences in core negative symptoms (alogia, avolition, flat affect), but do suggest that a cognition-related factor differs between Mexican American and Anglo American schizophrenic patients.
本研究旨在评估25名英裔美国人和26名墨西哥裔美国精神分裂症患者阴性症状特征的种族差异。在1 - 2周的药物洗脱期结束时（时间1）和出院时（时间2），使用阴性症状评估量表（NSA）、简明精神病学研究量表（BPRS）、《精神疾病诊断与统计手册》（第4版）（DSM-IV）阴性因子评分以及洛杉矶西班牙裔文化适应量表对受试者进行评定。在时间1和时间2时，墨西哥裔美国人的NSA总分均显著更高。在NSA的五个分量表中，仅在时间1时认知分量表存在显著的种族差异。结果表明，在核心阴性症状（言语贫乏、意志缺乏、情感平淡）方面不存在种族差异，但确实提示墨西哥裔美国和英裔美国精神分裂症患者之间存在与认知相关的因素差异。
