Kallas M R, Scaletsky I C, Fagundes-Neto U
Disciplina de Gastroenterologia Pediátrica, UNIFESP-EPM.
Arq Gastroenterol. 1997 Jan-Mar;34(1):62-8.
Enteropathogenic Escherichia coli. (EPEC) are gram negative bacteria of great importance in the etiology of diarrhea in children under two years of age living in developing countries. It was first reported in 1946. Its pathogenic mechanism was unknown until 1970 when several papers were published in the attempt to find out their physiophatologic mechanism. These bacteria interfere on the small bowel resulting in parcial or sub total villous atrophy. This injury will revert when the infection subsides.
肠致病性大肠杆菌(EPEC)是革兰氏阴性菌,在发展中国家两岁以下儿童腹泻病因中具有重要意义。它于1946年首次被报道。直到1970年,几篇论文发表试图找出其生理病理机制,其致病机制才为人所知。这些细菌干扰小肠,导致部分或完全绒毛萎缩。感染消退后,这种损伤会恢复。