van Gemert W G, Adang E M, Greve J W, Soeters P B
Department of Surgery, University Hospital Maastricht, The Netherlands.
Am J Clin Nutr. 1998 Feb;67(2):197-201. doi: 10.1093/ajcn/67.2.197.
The effect of surgically induced weight loss on the quality of life of morbidly obese patients was investigated in a controlled cross-sectional study. A postoperative group of 62 patients was compared with a control group of 20 preoperative patients. The Nottingham Health Profile part I (NHP-I) and part II (NHP-II) and a visual analogue scale were used for quality of life assessment. Significant differences were found on the NHP-II (P < 0.0001), the visual analogue scale (P < 0.001), and on the domains of mobility (P < 0.0001), energy (P < 0.001), and emotional reaction (P < 0.001) on the NHP-I in favor of the postoperative group. Better quality of life outcome was related to larger weight loss and shorter length of postoperative follow-up. No correlation was found between quality of life outcome and the type of surgical procedure or surgical complications. The unemployment rate was 53% for the overall postoperative group and 64% for the female postoperative group compared with 80% (P < 0.05) and 84% (NS) in the overall and female control groups, respectively. Overweight as the reason for unemployment was more frequent in the control group. The results of this study show that quality of life is better after surgically induced weight loss and is not related to the type of surgical procedure nor to surgical complications. Postoperative quality of life tends to decrease with time.
在一项对照横断面研究中,调查了手术引起的体重减轻对病态肥胖患者生活质量的影响。将62例术后患者组成的一组与20例术前患者组成的对照组进行比较。使用诺丁汉健康量表第一部分(NHP-I)和第二部分(NHP-II)以及视觉模拟量表来评估生活质量。在NHP-II(P < 0.0001)、视觉模拟量表(P < 0.001)以及NHP-I中的活动能力(P < 0.0001)、精力(P < 0.001)和情绪反应(P < 0.001)领域发现了有利于术后组的显著差异。更好的生活质量结果与更大的体重减轻和更短的术后随访时间有关。生活质量结果与手术程序类型或手术并发症之间未发现相关性。整个术后组的失业率为53%,女性术后组为64%,而整个对照组和女性对照组的失业率分别为80%(P < 0.05)和84%(无显著性差异)。对照组中因超重导致失业的情况更为常见。本研究结果表明,手术引起体重减轻后生活质量更好,且与手术程序类型和手术并发症均无关。术后生活质量往往会随着时间下降。