Alonso E, Maróstica A, Roma S, Redín I, Sánchez Mazzaferri F, Toffoni C
Instituto de Anatomía Patológica, Rosario, Argentina.
Arch Esp Urol. 1997 Oct;50(8):875-8.
To report a case of transitional cell carcinoma of the urethra associated with human papilloma virus (HPV) infection in areas of squamous differentiation of the neoplasm.
METHODS/RESULTS: A 32-year-old male with a previously treated condylomata acuminatum of the prepuce presented with a verrucous lesion in the penile meatus, corresponding to well differentiated, low grade papillary transitional cell carcinoma with squamous differentiation. Histological viral expression of HPV was confirmed by in situ hybridization.
We emphasize the rare presentation of transitional carcinoma in the distal urethra associated with HPV infection.
报告一例尿道移行细胞癌,该肿瘤鳞状分化区域与人乳头瘤病毒(HPV)感染相关。
方法/结果:一名32岁男性,既往有包皮尖锐湿疣病史,现阴茎尿道口出现疣状病变,病理为高分化、低级别乳头状移行细胞癌伴鳞状分化。原位杂交证实HPV的组织学病毒表达。
我们强调远端尿道移行细胞癌合并HPV感染的罕见表现。