Adrian R M
Center for Laser Surgery, Georgetown University Medical School, Washington, DC 20016, USA.
Dermatol Surg. 1998 Jan;24(1):19-23. doi: 10.1111/j.1524-4725.1998.tb04046.x.
At the present time a large variety of vascular lesion lasers are available for the treatment of both congenital and acquired disorders of blood vessels. Although most vascular lesions lasers are variably effective in the treatment of facial telangiectasias, port-wine stains, hemangiomas, and other vascular anomalies, their use in the treatment of leg veins has been disappointing. Histologic, anatomic, and other variables have been associated with a poor response of leg veins to currently available vascular lesion lasers.
This study examines the use of a new long pulse frequency-doubled Neodymium (Nd):YAG laser emitting radiation at 532 nm for the treatment of leg veins.
Fifty patients with leg telangiectasias of varying diameters were treated using a variable pulse width frequency doubled Nd:YAG laser. This laser delivers energy through a novel water-cooled chill tip, which appears to limit epidermal damage during laser treatment.
Sixty-two treatment sites were evaluated in 50 patients. Seventy-three percent of patients had greater than 50% improvement after one treatment. Eight-three percent were graded with clearances of better than 50% after two treatments, with 63% showing greater than 75% improvement.
The VersaPulse variable pulse width laser appears to be an effective modality for the treatment of leg telangiectasias. The relative lack of patient discomfort combined with a high degree of patient satisfaction may indicate a fairly high level of patient acceptance of this new form of therapy for the treatment of leg telangiectasias.
目前有多种血管病变激光可用于治疗先天性和后天性血管疾病。尽管大多数血管病变激光在治疗面部毛细血管扩张、葡萄酒色斑、血管瘤及其他血管异常方面有不同程度的疗效，但它们在治疗腿部静脉方面的效果却不尽人意。组织学、解剖学及其他变量与腿部静脉对现有血管病变激光反应不佳有关。
本研究探讨一种新型长脉冲倍频钕（Nd）:钇铝石榴石（YAG）激光（发射波长为532nm的辐射）在治疗腿部静脉中的应用。
使用可变脉宽倍频Nd:YAG激光对50例不同直径腿部毛细血管扩张患者进行治疗。该激光通过一种新型水冷冷却头传递能量，这似乎能在激光治疗期间限制表皮损伤。
对50例患者的62个治疗部位进行了评估。73%的患者在一次治疗后改善超过50%。83%的患者在两次治疗后清除率优于50%，其中63%改善超过75%。
VersaPulse可变脉宽激光似乎是治疗腿部毛细血管扩张的有效方式。患者相对较少的不适感以及较高的满意度可能表明患者对这种治疗腿部毛细血管扩张的新疗法接受程度较高。
