Major A, Brazzini B, Campolmi P, Bonan P, Mavilia L, Ghersetich I, Hercogova J, Lottit T
Department of Dermatology, University of Florence, Italy.
J Eur Acad Dermatol Venereol. 2001 Nov;15(6):559-65. doi: 10.1046/j.1468-3083.2001.00354.x.
Facial and leg telangiectasias are a frequent cosmetic concern for both females and males with various skin types and ages. To date the different treatments for these problems, in particular leg telangiectasias, have frequently failed or led to negative side-effects.
This study examines the clinical effects and safety of applications with a 1064-nm Nd:YAG laser system (SmartEpil II, DEKA M.e.l.a., Florence, Italy) to treat vessels on the face and legs.
Twenty-five subjects with facial telangiectasias underwent one treatment at 100 J/cm2, 10 ms and 2 Hz repetition rate. Thirty-two subjects with leg telangiectasias, measuring 0.1-3 mm in diameter, were treated at 125-200 J/cm2, 10-30 ms and 2 Hz repetition rate. Subjects in this group underwent one to five treatment sessions at 8 week intervals.
All subjects showed visible improvement, with 95-100% clearing of the face telangiectasias after only one treatment, and 50-100% clearing of the lower extremity vessels after three to five treatments. Transitory hypopigmentation was seen in two cases subjected to leg vessel treatment.
Treatment of facial and leg telangectasias using a true long pulse 1064 nm Nd:YAG laser is an effective and safe method. The relative lack of discomfort combined with a high degree of individual satisfaction should play a part in the fairly high level of acceptance of this new form of therapy for the treatment of leg and face telangiectasias.
面部和腿部毛细血管扩张是不同皮肤类型和年龄段的男性和女性常见的美容问题。迄今为止,针对这些问题的不同治疗方法,尤其是腿部毛细血管扩张的治疗,常常失败或导致负面副作用。
本研究探讨使用1064纳米掺钕钇铝石榴石激光系统(SmartEpil II,DEKA M.e.l.a.,意大利佛罗伦萨)治疗面部和腿部血管的临床效果和安全性。
25名面部毛细血管扩张患者接受了一次能量密度为100 J/cm²、脉宽为10毫秒、重复频率为2赫兹的治疗。32名直径为0.1 - 3毫米的腿部毛细血管扩张患者接受了能量密度为125 - 200 J/cm²、脉宽为10 - 30毫秒、重复频率为2赫兹的治疗。该组患者每隔8周接受1至5次治疗。
所有患者均有明显改善,仅一次治疗后面部毛细血管扩张清除率达95 - 100%,三至五次治疗后下肢血管清除率达50 - 100%。两名接受腿部血管治疗的患者出现了暂时性色素减退。
使用真正的长脉冲1064纳米掺钕钇铝石榴石激光治疗面部和腿部毛细血管扩张是一种有效且安全的方法。相对较少的不适感以及较高的个人满意度,应该有助于这种新的治疗方法在治疗腿部和面部毛细血管扩张方面获得较高的接受度。