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来自皮肤涂片部位的IgM抗酚糖脂-I抗体检测:与静脉抗体水平及细菌指数的相关性

IgM anti-phenolic glycolipid-I antibody measurements from skin-smear sites: correlation with venous antibody levels and the bacterial index.

作者信息

Butlin C R, Soares D, Neupane K D, Failbus S S, Roche P W

机构信息

Anandaban Leprosy Hospital, Kathmandu, Nepal.

出版信息

Int J Lepr Other Mycobact Dis. 1997 Dec;65(4):465-8.

PMID:9465156
Abstract

Measurements of anti-phenolic glycolipid-I antibodies were made in 200 matched samples of capillary blood from the skin-smear site, venous blood collected on filter paper, and sera. A close correlation among the three samples was observed and a weaker correlation among the antibody levels and the average and skin-smear bacterial index. Capillary blood from the skin-smear site had a consistently higher level of antibodies in each sample than did the sera. The collection of capillary blood from skin-smear sites is a convenient and economical method of obtaining samples for serology and for measuring local antibody levels, and it may be more sensitive than measurements of antibodies in sera.

摘要

对来自皮肤涂片部位的毛细血管血、滤纸上采集的静脉血以及血清的200对匹配样本进行了抗酚糖脂-I抗体检测。观察到这三种样本之间存在密切相关性,而抗体水平与平均及皮肤涂片细菌指数之间的相关性较弱。在每个样本中,来自皮肤涂片部位的毛细血管血中的抗体水平始终高于血清。从皮肤涂片部位采集毛细血管血是一种方便且经济的获取血清学样本和测量局部抗体水平的方法,并且它可能比检测血清中的抗体更敏感。

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