Wilson S M, Goss S, Drobniewski F
Public Health Laboratory Service Mycobacterium Reference Unit, Dulwich Hospital, East Dulwich Grove, East Dulwich, London SE22 8QF, United Kingdom.
J Clin Microbiol. 1998 Nov;36(11):3385-8. doi: 10.1128/JCM.36.11.3385-3388.1998.
We have investigated the role of two rapid PCR-based typing methods, IS6110-based PCR and spacer-oligonucleotide typing, within a national tuberculosis reference service. The validity of clusters with IS6110 restriction fragment length polymorphism fingerprints with less than 6 bands was also investigated in the context of referred isolates.
我们在一个国家结核病参考服务机构中研究了两种基于快速聚合酶链反应(PCR)的分型方法,即基于IS6110的PCR和间隔区寡核苷酸分型的作用。在送检分离株的背景下,还研究了IS6110限制性片段长度多态性指纹图谱中条带少于6条的聚类的有效性。