Seifi H A, Karimi K, Movasseghi A R
Department of Clinical Sciences, School of Veterinary Medicine, Ferdowsi University of Mashhad, Iran.
Zentralbl Veterinarmed B. 1997 Dec;44(10):631-3. doi: 10.1111/j.1439-0450.1997.tb01017.x.
Renal amyloidosis is a rare condition in cattle and this report is the first in Iran. A 5-year old Holstein cow was referred because of profuse diarrhoea, ventral oedema and decreased appetite. Physical examination revealed a well audible ping area on the upper half of the right paralumbar fossa. At rectal examination, a large firm and circular shaped kidney was palpated. Laboratory examination revealed hypoproteinaemia and severe proteinuria. At necropsy, the kidneys were enlarged, yellow and waxy. Amyloid deposits were found in glomeruli by microscopic examination of the kidneys, and with Congo red staining renal amyloidosis was confirmed.
肾淀粉样变性在牛中是一种罕见病症，本报告是伊朗的首例。一头5岁的荷斯坦奶牛因严重腹泻、腹部水肿和食欲减退前来就诊。体格检查发现右腰旁窝上半部分有一个清晰可闻的叩诊区。直肠检查时，触诊到一个大的、坚硬且呈圆形的肾脏。实验室检查显示低蛋白血症和严重蛋白尿。尸检时，肾脏肿大、呈黄色且质地如蜡。通过对肾脏进行显微镜检查，在肾小球中发现了淀粉样沉积物，经刚果红染色确诊为肾淀粉样变性。
