Fields W S, Lemak N A
JAMA. 1976 Jun 14;235(24):2608-10.
This prospective analysis of 79 patients with transient carotid ischemic attacks (TIAs) showed that only 15% of them subsequently had strokes causing serious disability or death. They were followed up from one to nine years. All had arteriography during initial evaluation. Most of the patients who suffered strokes had at least one additional risk factor for stroke, such as hypertension or a cardiac problem. Today it is probably impossible to collect data on the natural history of untreated TIAs, inasmuch as virtually all patients are receiving either specific medical or surgical therapy.
这项对79例短暂性脑缺血发作(TIA)患者的前瞻性分析表明,其中只有15%的患者随后发生了导致严重残疾或死亡的中风。他们接受了1至9年的随访。所有患者在初次评估时均进行了动脉造影。大多数发生中风的患者至少还有一种中风的额外危险因素,如高血压或心脏问题。如今,要收集未经治疗的TIA自然病史的数据可能是不可能的,因为几乎所有患者都在接受特定的药物或手术治疗。