Aquadro C F
Cornell University, Section of Genetics and Development, Ithaca, New York 14853, USA.
Curr Opin Genet Dev. 1997 Dec;7(6):835-40. doi: 10.1016/s0959-437x(97)80048-2.
Studies of DNA sequence diversity, particularly in Drosophila, reveal both the complexity of natural selection and the importance of the interaction of natural selection and variation in rates of recombination within genomes and between species in determining levels of sequence variability in different genes and different species. The impact of both adaptive and deleterious mutations are evident. Extension of these types of studies to other organisms has begun in earnest.
对DNA序列多样性的研究，尤其是对果蝇的研究，揭示了自然选择的复杂性，以及自然选择与基因组内和物种间重组率变化之间的相互作用在决定不同基因和不同物种的序列变异性水平方面的重要性。适应性突变和有害突变的影响都很明显。这类研究向其他生物体的扩展已认真展开。
