Casasnovas Lenguas J A, Crussells Canales M J, Pelegrín Díaz J, Ferreira Aguar A, Serrano Aísa P J, del Río Ligorit A, Elósegui Elorza L M, Celma Delgado T, Arcarazo García L A, Cuenca Campillo J A, Giner Soria A, Ferreira Montero I J
Servicio de Cardiología, Hospital Clínico Universitario Lozano Blesa, Zaragoza.
Rev Esp Cardiol. 1997 Dec;50(12):843-50.
There is controversy in determining the effects of olive oil in the lipidic metabolism. We studied the changes produced in the lipid profile after substituting sunflower dietetic oil with virgin olive oil.
We studied 154 cadets of Academia General Militar de Zaragoza (AGEMZA), analyzing their smoking habits, anthropometric measures and dietetic intake. Hematologic, biochemical and lipidic parameters were determined in venous blood samples. All sunflower dietetic oil was substituted with olive oil, without making any other qualitative-quantitative variation in the diet 10 weeks after which the morphometric and analytical evaluation was repeated, comparing both measurements.
87% of cadets took part in the study. 34.3% of them were smokers. There were no significant anthropometric changes. After the interventional period, there was a decrease of 12.2% in total cholesterol (166.6 vs 146.2 mg/dl; p < 0.0001), 13.5% in LDL-cholesterol (99.7 vs 86.2 mg/dl; p < 0.0001), 12.2% in triglycerides (71.1 vs 62.4 mg/dl; p < 0.0001), 9.9% in HDL-cholesterol (52.6 vs 47.4 mg/dl; p < 0.001), despite which total-cholesterol/HDL-cholesterol ratio increased 3.1% (3.2 +/- 0.7 vs 3.1 +/- 0.7; p < 0.001). There were no changes in Lp(a) plasmatic concentrations or hematologic or biochemical parameters.
The improvement of the lipidic parameters can only be explained by the use of olive oil in the diet of the AGEMZA cadets.
在确定橄榄油对脂质代谢的影响方面存在争议。我们研究了用初榨橄榄油替代葵花籽食用植物油后血脂谱的变化。
我们研究了萨拉戈萨综合军事学院（AGEMZA）的154名学员，分析了他们的吸烟习惯、人体测量指标和饮食摄入情况。测定静脉血样本中的血液学、生化和脂质参数。将所有葵花籽食用植物油都替换为橄榄油，饮食在定性和定量方面均未作其他改变，10周后重复进行形态测量和分析评估，并对两次测量结果进行比较。
87%的学员参与了研究。其中34.3%为吸烟者。人体测量指标无显著变化。干预期后，总胆固醇降低了12.2%（从166.6降至146.2mg/dl；p<0.0001），低密度脂蛋白胆固醇降低了13.5%（从99.7降至86.2mg/dl；p<0.0001），甘油三酯降低了12.2%（从71.1降至62.4mg/dl；p<0.0001），高密度脂蛋白胆固醇降低了9.9%（从52.6降至47.4mg/dl；p<0.001），尽管如此，总胆固醇/高密度脂蛋白胆固醇比值仍升高了3.1%（从3.2±0.7升至3.1±0.7；p<0.001）。血浆Lp(a)浓度以及血液学或生化参数均无变化。
脂质参数的改善只能通过在AGEMZA学员饮食中使用橄榄油来解释。
