Lavigne S E, Gutenkunst L S, Williams K B
Department of Dental Hygiene, Wichita State University, Kansas, USA.
J Dent Hyg. 1997 May-Jun;71(3):105-11.
The purpose of this three-week, double-blind pilot study was to assess the effects of a tartar-control dentifrice on tooth sensitivity.
Fifty-six volunteer dental hygiene students completed a 14-item questionnaire regarding their oral health. Eighteen students were excluded from the study due to prior tooth sensitivity. Thirty-eight students were randomly assigned to either the experimental group using a tartar-control dentifrice (containing tetrapotassium pyrophosphate, PEG-6, disodium pyrophosphate, and tetrasodium pyrosulphate in a 5.0% soluble pyrophosphate formulation) or the control group using a regular dentifrice. Participants brushed for three weeks twice daily and then completed a post-treatment questionnaire, which included questions about tooth sensitivity. Differences between groups in reported sensitivity were measured by Fisher's Exact Test.
Fisher's Exact Test revealed a statistically significant difference in sensitivity experienced by the experimental group compared to the control group (p < 0.05), which reported no sensitivity. The phi coefficient, used to examine the strength of the relationship between tartar control paste and tooth sensitivity, was found significant at p < 0.02.
These findings suggest that patients may experience dentinal hypersensitivity when using the tartar-control toothpaste tested. Further long-term studies are required to test various brands of tartar-control dentifrice with a larger, more diverse sample for clinical measures of sensitivity.
这项为期三周的双盲试点研究旨在评估一款防牙垢牙膏对牙齿敏感性的影响。
56名牙科保健专业的志愿者学生完成了一份关于他们口腔健康的14项问卷。18名学生因之前有牙齿敏感问题被排除在研究之外。38名学生被随机分配到使用防牙垢牙膏(含5.0%可溶性焦磷酸盐配方的焦磷酸四钾、聚乙二醇-6、焦磷酸二钠和焦硫酸四钠)的实验组或使用普通牙膏的对照组。参与者每天刷牙两次,持续三周,然后完成一份治疗后问卷,其中包括有关牙齿敏感性的问题。通过Fisher精确检验测量两组报告的敏感性差异。
Fisher精确检验显示,与未报告有敏感性的对照组相比,实验组经历的敏感性存在统计学上的显著差异(p < 0.05)。用于检验防牙垢牙膏与牙齿敏感性之间关系强度的phi系数在p < 0.02时具有显著性。
这些发现表明,患者在使用所测试的防牙垢牙膏时可能会出现牙本质过敏。需要进一步进行长期研究,以使用更大、更多样化的样本测试各种品牌的防牙垢牙膏,进行敏感性的临床测量。