Hubler W R, Wolf J E
Cancer. 1976 Jul;38(1):187-92. doi: 10.1002/1097-0142(197607)38:1<187::aid-cncr2820380129>3.0.co;2-d.
Transparent hamster-cheek-pouch chambers were used to document angiogenesis induced by implants of human malignant melanoma. Capillary proliferation was observed with direct implantation of melanoma fragments and with tumor implants place on microporous membrane filters. The pattern of capillary neovascularization was recorded and correlated with clinical and histopathologic parameters.
使用透明的仓鼠颊囊室来记录人类恶性黑色素瘤植入物诱导的血管生成。通过直接植入黑色素瘤碎片以及将肿瘤植入微孔膜滤器上观察到了毛细血管增殖。记录了毛细血管新生血管形成的模式,并将其与临床和组织病理学参数相关联。