Stenninger E, Schollin J, Aman J
Department of Paediatrics, Orebro Medical Centre Hospital, Sweden.
Acta Paediatr. 1997 Dec;86(12):1374-6. doi: 10.1111/j.1651-2227.1997.tb14916.x.
This study found that early postnatal hypoglycaemia was mainly induced by foetal hyperinsulinaemia, in close relation to maternal hyperglycaemia, even in well-controlled pregnancies of 59 mothers with insulin-treated diabetes mellitus, 29 with insulin-dependent diabetes mellitus and 30 with gestational diabetes mellitus. Ten of the newborn children (17%) had a blood glucose concentration below 1.0 mmol l(-1) at 2 h postnatally. Cord insulin-like growth factor-I or glucagon concentrations were not related to the early decline of blood glucose.
本研究发现，即使在59例接受胰岛素治疗的糖尿病母亲、29例胰岛素依赖型糖尿病母亲和30例妊娠糖尿病母亲血糖控制良好的妊娠中，产后早期低血糖主要由胎儿高胰岛素血症引起，且与母亲高血糖密切相关。10名新生儿（17%）在出生后2小时血糖浓度低于1.0 mmol l(-1)。脐血胰岛素样生长因子-I或胰高血糖素浓度与血糖早期下降无关。
