Singh R B, Rastogi S S, Rao P V, Das S, Madhu S V, Das A K, Sahay B K, Fuse S M, Beegom R, Sainani G S, Shah N A
Centre of Nutrition, Medical Hospital and Research Centre, Moradabad, India.
J Cardiovasc Risk. 1997 Jun;4(3):201-8.
There has been a rapid increase in the prevalence of diabetes and cardiovascular disease in India, in association with rapid changes in diet and lifestyle. In adults, the prevalence of diabetes, hypertension and coronary artery disease is two- to threefold greater in the urban population than in rural populations; it is associated with modest insulin resistance in urban groups.
In response to a proposal by the International College of Nutrition that specialist experts should develop consensus recommendations for the prevention of chronic diseases, Indian specialists in diabetes and vascular disease have collaborated to produce guidelines relevant to the population of India.
Because Indian urban populations have a modest increase in overweight and low rates of obesity in association with the rapid emergence of diabetes and cardiovascular risk, a body mass index of 21 kg/m2 should be considered safe, with a range of 19-23 kg/m2 acceptable; > 23 kg/m2 should be considered overweight, and > 25 kg/m2 should be taken to indicate obesity. A waist:hip ratio > 0.88 in males and > 0.85 in females should be considered to indicate central obesity, because the prevalence of coronary disease, hypertension and associated disturbances of insulin resistance are more common above these limits. For the prevention of vascular disease, there is general international consensus that the desirable serum concentration of cholesterol should be < 170 mg/dl (> 4.42 mmol/l), which may also be optimal for Indians; values between 170 and 200 mg/dl (4.42-5.2 mmol/l) should be considered borderline. The critical values for low density lipoprotein cholesterol may be < 90 mg/dl (ideal), 90-110 mg/dl (borderline high) and > 110 mg/dl (high) (< 2.32, 2.32-2.84 and > 2.84 mmol/l, respectively). Fasting triglycerides should be < 150 mg/dl (< 1.69 mmol/l) and high-density lipoprotein cholesterol > 35 mg/dl (> 0.9 mmol/l). The limit for the total energy derived from fat intake should be < 21%/day (7% each for saturated, polyunsaturated and mono-unsaturated fatty acids). The carbohydrate intake should provide more than 65% of daily energy, mainly from complex carbohydrates. A daily dietary intake of 400 g fruits, vegetables and legumes, 400 g cereals, in conjunction with 25 g soya bean or mustard or canola oils (rich in n-3 fatty acids) in place of fats rich in saturated fat, may be protective against diabetes and vascular disease. Moderate physical activity with the aim of burning 300 Kcal/day (> 1255 KJ/day), and cessation of tobacco and alcohol consumption, may provide an effective programme for prevention of diabetes and its vascular complications in Indians.
随着饮食和生活方式的迅速改变,印度糖尿病和心血管疾病的患病率急剧上升。在成年人中,城市人口的糖尿病、高血压和冠状动脉疾病患病率比农村人口高出两到三倍;这与城市人群中适度的胰岛素抵抗有关。
应国际营养学院提出的专家应制定慢性病预防共识建议的提议,印度糖尿病和血管疾病专家合作制定了与印度人群相关的指南。
由于印度城市人口超重略有增加且肥胖率较低,同时糖尿病和心血管疾病风险迅速出现,体重指数21kg/m²应被视为安全范围,19 - 23kg/m²可接受;>23kg/m²应被视为超重,>25kg/m²应被视为肥胖。男性腰臀比>0.88、女性>0.85应被视为中心性肥胖,因为冠心病、高血压及相关胰岛素抵抗紊乱在这些界限以上更为常见。对于血管疾病的预防,国际上普遍共识是理想的血清胆固醇浓度应<170mg/dl(>4.42mmol/l),这对印度人可能也是最佳的;170 - 200mg/dl(4.42 - 5.2mmol/l)应被视为临界值。低密度脂蛋白胆固醇的临界值可能为<90mg/dl(理想)、90 - 110mg/dl(临界高)和>110mg/dl(高)(分别为<2.32、2.32 - 2.84和>2.84mmol/l)。空腹甘油三酯应<150mg/dl(<1.69mmol/l),高密度脂蛋白胆固醇>35mg/dl(>0.9mmol/l)。脂肪摄入所提供的总能量上限应为<21%/天(饱和、多不饱和和单不饱和脂肪酸各占7%)。碳水化合物摄入应提供每日能量的65%以上,主要来自复合碳水化合物。每日饮食摄入400g水果、蔬菜和豆类、400g谷物,同时用25g富含n - 3脂肪酸的大豆油、芥菜籽油或菜籽油替代富含饱和脂肪的油脂,可能对预防糖尿病和血管疾病有保护作用。以每天消耗300千卡热量(>1255千焦)为目标的适度体育活动,以及戒烟戒酒,可能为预防印度人的糖尿病及其血管并发症提供有效方案。