Fogari R, Zoppi A, Marasi G, Preti P, Mugellini A, Vanasia A, Lusardi P
Department of Internal Medicine and Therapeutics, University of Pavia, Italy.
J Cardiovasc Risk. 1997 Jun;4(3):209-13.
To evaluate heart rate and its relationship with some established cardiovascular risk factors in normotensive and hypertensive individuals.
We studied 881 1 men, 696 with essential hypertension and 8115 with normal blood pressure, stratified in four age groups: 20-29, 30-39, 40-49 and 50-59 years. Clinical evaluation included measures of heart rate (by pulse palpation), blood pressure (by mercury sphygmomanometer), total cholesterol, triglycerides, blood glucose and fibrinogen, and details of medical history and personal habits, with particular regard to smoking habits.
Heart rate, which was significantly higher in hypertensive than in normotensive individuals, showed no significant change with age in the normotensive group, but a slight decline with increasing age in those with hypertension. In the normotensive group, heart rate was significantly higher in smokers than in non-smokers and ex-smokers, and showed no significant variation with increasing age, independently of smoking habits. Among those with hypertension, heart rate was not statistically different in smokers, non-smokers and ex-smokers, and showed a moderate decrease with age in non-smokers and ex-smokers, but did not change with age in smokers.
Both ageing and smoking habits have different effects on heart rate in normotensive and hypertensive individuals.
评估正常血压和高血压个体的心率及其与一些已确定的心血管危险因素的关系。
我们研究了8811名男性,其中696名患有原发性高血压,8115名血压正常,分为四个年龄组:20 - 29岁、30 - 39岁、40 - 49岁和50 - 59岁。临床评估包括心率测量(通过脉搏触诊)、血压测量(通过汞柱式血压计)、总胆固醇、甘油三酯、血糖和纤维蛋白原,以及病史和个人习惯细节,尤其关注吸烟习惯。
高血压个体的心率显著高于正常血压个体,正常血压组的心率随年龄无显著变化,但高血压患者的心率随年龄略有下降。在正常血压组中,吸烟者的心率显著高于非吸烟者和已戒烟者,且与年龄增长无关,不受吸烟习惯影响。在高血压患者中,吸烟者、非吸烟者和已戒烟者的心率无统计学差异,非吸烟者和已戒烟者的心率随年龄适度下降,但吸烟者的心率不随年龄变化。
衰老和吸烟习惯对正常血压和高血压个体的心率有不同影响。