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衣原体感染与男性不育

Chlamydial infections and male infertility.

作者信息

Cengiz T, Aydoğanli L, Baykam M, Mungan N A, Tunçbilek E, Dinçer M, Yakupoğlu K, Akalin Z

机构信息

1st Department of Urology, Ankara Numune Hospital, Ministry of Health, Turkey.

出版信息

Int Urol Nephrol. 1997;29(6):687-93. doi: 10.1007/BF02552187.

DOI:10.1007/BF02552187
PMID:9477368
Abstract

Chlamydial infections may be difficult to diagnose due to the silent symptoms and difficulty in culturing. An infectious process may impair fertility by adversely affecting sperm functions, resulting in testicular damage or causing obstruction of the genital tract. In our study, we tried to find Chlamydial antigen by using EIA (Enzyme Immune Assay) and to compare the Ag(+) and Ag(-) groups according to semen parameters. Except for semen volume, we found significant differences in density, morphology, motility and viability (intervolume p > 0.05, interdensity p < 0.01, intermorphology p < 0.001, intermotility p < 0.001 and interviability p < 0.001).

摘要

由于衣原体感染症状不明显且培养困难,其感染可能难以诊断。感染过程可能会通过对精子功能产生不利影响而损害生育能力,导致睾丸损伤或引起生殖道阻塞。在我们的研究中,我们试图通过酶免疫测定法(EIA)检测衣原体抗原,并根据精液参数比较抗原阳性(Ag(+))和抗原阴性(Ag(-))组。除精液量外,我们发现密度、形态、活力和存活率存在显著差异(精液量组间p>0.05,密度组间p<0.01,形态组间p<0.001,活力组间p<0.001,存活率组间p<0.001)。

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引用本文的文献

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Molecular detection of Chlamydia trachomatis and other sexually transmitted bacteria in semen of male partners of infertile couples in Tunisia: the effect on semen parameters and spermatozoa apoptosis markers.

本文引用的文献

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Infection and pyospermia in male infertility.男性不育中的感染与脓精症
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Coincubation of human spermatozoa with Chlamydia trachomatis in vitro causes increased tyrosine phosphorylation of sperm proteins.人精子与沙眼衣原体在体外共同孵育会导致精子蛋白酪氨酸磷酸化增加。
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Urol Clin North Am. 1994 Aug;21(3):469-75.
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Relationship between genital tract infections, sperm antibodies in seminal fluid, and infertility.生殖道感染、精液中的精子抗体与不孕症之间的关系。
Fertil Steril. 1983 Dec;40(6):805-8. doi: 10.1016/s0015-0282(16)47484-4.
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Fertil Steril. 1984 Jul;42(1):102-7. doi: 10.1016/s0015-0282(16)47966-5.
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