Suppr超能文献

[巴伊亚州的人类嗜T淋巴细胞病毒I型/II型感染]

[HTLV-I/II infection in the state of Bahia].

作者信息

Britto A P, Galvão-Castro B, Straatmann A, Santos-Torres S, Tavares-Neto J

机构信息

Faculdade de Medicina da Universidade Federal da Bahia, Salvador.

出版信息

Rev Soc Bras Med Trop. 1998 Jan-Feb;31(1):35-41. doi: 10.1590/s0037-86821998000100005.

Abstract

The city of Salvador, capital of Bahia, presents a population with the highest prevalence of HTLV-I infection in Brazil. Until now, only one study has investigated this infection in other cities of this state, even though by using a small sample. With objective to evaluate the prevalence of HTLV-I/II antibodies in four cities of the state of Bahia. Serum samples from 1,539 individuals who lived in Catolândia, Ipupiara, Jacobina and Prado were screened by ELISA, and repeatedly reactive samples confirmed by Western Blot. Forty-seven (3.1%) samples were positive by ELISA, and 44 of them were tested by Western blot: 5 (0.3%) were positive, 8 (0.5%) were indeterminate (all of them from Jacobina) and 31 were negative. The overall prevalence of HTLV-I antibodies was 0.3%. This prevalence varied from 0.0% (Prado) to 0.7% (Jacobina), but differences were not statistically significant (p > 0.21). None of these individuals presented HTLV-II antibodies. Jacobina showed the highest prevalence of HTLV-I infection among the cities studied, although the overall prevalence was low. In conclusion, further epidemiological, clinical and virological studies will be of paramount importance to obtain a better understanding of the natural history of this infection in Jacobina.

摘要

巴伊亚州首府萨尔瓦多市的居民是巴西HTLV-I感染率最高的人群。到目前为止,尽管样本量较小,但仅有一项研究对该州其他城市的这种感染情况进行了调查。目的是评估巴伊亚州四个城市中HTLV-I/II抗体的流行情况。采用酶联免疫吸附测定法(ELISA)对1539名居住在卡托兰迪亚、伊普皮阿拉、雅科比纳和普拉多的个体的血清样本进行筛查,对多次反应性样本采用蛋白质印迹法进行确认。酶联免疫吸附测定法检测出47份(3.1%)样本呈阳性,其中44份进行了蛋白质印迹法检测:5份(0.3%)呈阳性,8份(0.5%)结果不确定(均来自雅科比纳),31份呈阴性。HTLV-I抗体的总体流行率为0.3%。该流行率从0.0%(普拉多)到0.7%(雅科比纳)不等,但差异无统计学意义(p>0.21)。这些个体均未检测出HTLV-II抗体。在所研究的城市中,雅科比纳的HTLV-I感染率最高,尽管总体感染率较低。总之,进一步开展流行病学、临床和病毒学研究对于更好地了解雅科比纳这种感染的自然史至关重要。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验