Spearing M K, Post R M, Leverich G S, Brandt D, Nolen W
NIMH/BPB, NIH, Bethesda, MD 20892-1272, USA.
Psychiatry Res. 1997 Dec 5;73(3):159-71. doi: 10.1016/s0165-1781(97)00123-6.
The Clinical Global Impressions Scale (CGI) was modified specifically for use in assessing global illness severity and change in patients with bipolar disorder. Criticisms of the original CGI were addressed by correcting inconsistencies in scaling, identifying time frames for comparison, clarifying definitions of illness severity and change, and separating out assessment of treatment side effects from illness improvement during treatment. A Detailed User's Guide was developed to train clinicians in the use of the new CGI-Bipolar Version (CGI-BP) for rating severity of manic and depressive episodes and the degree of change from the immediately preceding phase and from the worst phase of illness. The revised scale and manual provide a focused set of instructions to facilitate the reliability of these ratings of mania, depression, and overall bipolar illness during treatment of an acute episode or in longer-term illness prophylaxis. Interrater reliability of the scale was demonstrated in preliminary analyses. Thus, the modified CGI-BP is anticipated to be more useful than the original CGI in studies of bipolar disorder.
临床总体印象量表（CGI）经过专门修改，用于评估双相情感障碍患者的整体疾病严重程度和变化。通过纠正量表中的不一致性、确定比较的时间框架、明确疾病严重程度和变化的定义，以及在治疗期间将治疗副作用评估与疾病改善评估分开，解决了对原始CGI的批评。制定了一份详细的用户指南，以培训临床医生使用新的双相情感障碍版本的CGI（CGI-BP）来评定躁狂和抑郁发作的严重程度，以及与紧接的前一阶段和疾病最严重阶段相比的变化程度。修订后的量表和手册提供了一套重点明确的说明，以提高在急性发作治疗或长期疾病预防期间对躁狂、抑郁和双相情感障碍整体评定的可靠性。在初步分析中证明了该量表的评定者间信度。因此，预计在双相情感障碍研究中，修改后的CGI-BP比原始CGI更有用。
