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牙源性牙瘤:104例回顾性研究

Dental odontomas: a retrospective study of 104 cases.

作者信息

Owens B M, Schuman N J, Mincer H H, Turner J E, Oliver F M

机构信息

Department of General Dentistry, University of Tennessee, College of Dentistry, Memphis 38163, USA.

出版信息

J Clin Pediatr Dent. 1997 Spring;21(3):261-4.

PMID:9484137
Abstract

An odontoma refers to any tumor of odontogenic origin. Three distinct types of odontomas have been distinguished in the dental literature: complex, compound, and ameloblastic fibro-odontoma. Odontomas are usually associated with overly retained primary and unerupted permanent teeth. The exact etiology of odontomas is unknown, but local trauma, infection, inheritance, and genetic mutation have been postulated as possible causes of odontomas. Studies have found that males are more likely than females to have odontomas, with most frequent occurrence in the second decade of life. One hundred four biopsy reports with a diagnosis of odontoma were analyzed for age, race, gender, location, pre-operative diagnosis, and postoperative laboratory findings. Most odontomas occurred in the 11-20 age group, with Caucasians predominating. The majority were located in the maxilla, and 85 percent were correctly diagnosed clinically by the attending dentist prior to confirmation by histologic pathology reports of the biopsy specimens. The vast majority were compound odontomas (64.4%) with complex odontomas comprising 31.0% of the total lesions. No ameloblastic fibro-odontomas were diagnosed.

摘要

牙瘤是指任何起源于牙源性的肿瘤。在牙科文献中已区分出三种不同类型的牙瘤:复合性牙瘤、组合性牙瘤和成釉细胞纤维牙瘤。牙瘤通常与过度滞留的乳牙和未萌出的恒牙有关。牙瘤的确切病因尚不清楚,但局部创伤、感染、遗传和基因突变被认为是牙瘤可能的病因。研究发现,男性比女性更易患牙瘤,最常见于生命的第二个十年。对104份诊断为牙瘤的活检报告进行了年龄、种族、性别、位置、术前诊断和术后实验室检查结果的分析。大多数牙瘤发生在11至20岁年龄组,以白种人为主。大多数位于上颌骨,85%在活检标本的组织病理学报告确认之前,经主治牙医临床正确诊断。绝大多数是组合性牙瘤(64.4%),复合性牙瘤占全部病变的31.0%。未诊断出成釉细胞纤维牙瘤。

相似文献

1
Dental odontomas: a retrospective study of 104 cases.牙源性牙瘤:104例回顾性研究
J Clin Pediatr Dent. 1997 Spring;21(3):261-4.
2
Odontoma: a clinicopathologic study of 81 cases.牙瘤:81例临床病理研究
J Formos Med Assoc. 2003 Dec;102(12):876-82.
3
An analysis of compound and complex odontomas.复合性和复杂性牙瘤的分析
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Clinicoradiopathologic Analysis of Odontomas: A Retrospective Study of 242 Cases.牙瘤的临床放射病理分析:242例回顾性研究
Dent J (Basel). 2023 Oct 30;11(11):253. doi: 10.3390/dj11110253.
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[Radiographic study of odontomas].[牙瘤的影像学研究]
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Metaanalysis of the epidemiology and clinical manifestations of odontomas.牙瘤流行病学及临床表现的Meta分析
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Odontomas: a clinicopathologic study in a Portuguese population.牙瘤:葡萄牙人群的临床病理研究
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Clinical and radiological profile of ameloblastic fibro-odontoma: an update on an uncommon odontogenic tumor based on a critical analysis of 114 cases.成釉细胞纤维牙瘤的临床和影像学特征:基于114例病例的批判性分析对一种罕见牙源性肿瘤的最新研究
Head Neck Pathol. 2013 Mar;7(1):54-63. doi: 10.1007/s12105-012-0397-9. Epub 2012 Sep 22.
9
An analysis of the interrelationship of the mixed odontogenic tumors--ameloblastic fibroma, ameloblastic fibro-odontoma, and the odontomas.混合性牙源性肿瘤——成釉细胞纤维瘤、成釉细胞纤维牙瘤和牙瘤的相互关系分析。
Oral Surg Oral Med Oral Pathol. 1981 Mar;51(3):266-76. doi: 10.1016/0030-4220(81)90056-6.
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[Clinical course, histology and prognostic assessment of odontomas].[牙瘤的临床病程、组织学及预后评估]
Dtsch Zahnarztl Z. 1991 Jan;46(1):68-70.

引用本文的文献

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A Rare Case Report of Unusual Number of Compound Odontomas in a Pediatric Patient.一名儿科患者出现罕见数量复合性牙瘤的病例报告
Int J Clin Pediatr Dent. 2024 Apr;17(4):497-500. doi: 10.5005/jp-journals-10005-2827.
2
Management of Mandibular Compound Odontoma With Numbness in the Lower Jaw.下颌复合牙瘤伴下颌麻木的治疗
Cureus. 2023 Dec 30;15(12):e51315. doi: 10.7759/cureus.51315. eCollection 2023 Dec.
3
Clinicoradiopathologic Analysis of Odontomas: A Retrospective Study of 242 Cases.牙瘤的临床放射病理分析:242例回顾性研究
Dent J (Basel). 2023 Oct 30;11(11):253. doi: 10.3390/dj11110253.
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Compound and Complex Odontomes: Case Series with Surgical Management and Brief Review of Literature.复合性和复杂性牙瘤:手术治疗的病例系列及文献简要综述
J Pharm Bioallied Sci. 2021 Nov;13(Suppl 2):S1772-S1777. doi: 10.4103/jpbs.jpbs_270_21. Epub 2021 Nov 10.
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Surgical Removal of Odontoma: A Case Report.牙瘤的手术切除:一例报告
Int J Clin Pediatr Dent. 2020;13(Suppl 1):S122-S124. doi: 10.5005/jp-journals-10005-1889.
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Sequential Removal of a Large Odontoma in the Angle of the Mandible.下颌角大型牙瘤的序贯性切除
Ann Maxillofac Surg. 2019 Jul-Dec;9(2):429-433. doi: 10.4103/ams.ams_102_19.
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Compound Odontome: A Case Report.复合性牙瘤:一例报告
Int J Clin Pediatr Dent. 2019 Jan-Feb;12(1):64-67. doi: 10.5005/jp-journals-10005-1575.
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Rare case of bilateral complex odontoma associated with mandibular bicuspids.罕见的双侧复合性牙瘤伴下颌双尖牙病例。
Dent Res J (Isfahan). 2018 May-Jun;15(3):220-223.
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Odontogenic tumors in Port Harcourt: South-South geopolitical zone of Nigeria.哈科特港的牙源性肿瘤:尼日利亚南南地缘政治区
J Oral Maxillofac Pathol. 2016 May-Aug;20(2):190-3. doi: 10.4103/0973-029X.185934.
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Activated WNT signaling in postnatal SOX2-positive dental stem cells can drive odontoma formation.出生后SOX2阳性牙干细胞中激活的WNT信号传导可驱动牙瘤形成。
Sci Rep. 2015 Sep 28;5:14479. doi: 10.1038/srep14479.