Uchuya M, Fleury A, Graus F, Costagliola D, Liblau R, Merle-Beral H, Théodorou I, Delattre J Y
Department of Neurology, Hôpital de la Salpêtrière, Paris, France.
Neurology. 1998 Feb;50(2):565-6. doi: 10.1212/wnl.50.2.565.
We compared the human leukocyte antigen alleles found in a group of 17 patients with small-cell lung cancer (SCLC), paraneoplastic neurologic syndromes (PNS), and high titers of anti-Hu autoantibodies with those in 30 patients with SCLC but no PNS and no anti-Hu antibodies (control group). There was no difference between the two groups, suggesting that specific haplotypes are not required for the development of the "anti-Hu syndrome."
我们比较了一组17例患有小细胞肺癌(SCLC)、副肿瘤性神经综合征(PNS)且抗Hu自身抗体滴度高的患者与30例患有SCLC但无PNS且无抗Hu抗体的患者(对照组)中发现的人类白细胞抗原等位基因。两组之间没有差异,这表明“抗Hu综合征”的发生不需要特定的单倍型。