戊巴比妥麻醉：对犬静脉前列腺素无影响
Pentobarbital anesthesia: lack of effect on venous prostaglandins in dogs.
作者信息
Berger H J, Speroff L, Wolfson S
出版信息
Prostaglandins. 1976 Mar;11(3):499-502. doi: 10.1016/0090-6980(76)90096-4.
PMID:948622
Abstract
Venous prostaglandins A, E, and F were determined by radioimmunoassay in 10 dogs before and one hour after administration of sodium pentobarbital (35 mg/Kg, iv). In the conscious state, PGA was 0.34 + 0.04 ng/ml (mean +/- SE), PGE 0.20 + 0.01 ng/ml, and PGF 0.25 + 0.03 ng/ml. During pentobarbital anesthesia, these levels were unchanged (p greater than 0.05). Thus, pentobarbital anesthesia had no effect on peripheral venous prostaglandin levels.
摘要
采用放射免疫分析法测定了10只犬静脉注射戊巴比妥钠（35毫克/千克，静脉注射）前及注射后1小时静脉中前列腺素A、E和F的含量。在清醒状态下，前列腺素A为0.34±0.04纳克/毫升（均值±标准误），前列腺素E为0.20±0.01纳克/毫升，前列腺素F为0.25±0.03纳克/毫升。在戊巴比妥麻醉期间，这些水平未发生变化（p＞0.05）。因此，戊巴比妥麻醉对外周静脉前列腺素水平无影响。
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