Gilbertson E O, Spellman M C, Piacquadio D J, Mulford M I
Department of Medicine, UCSD School of Medicine, San Diego, California, USA.
J Am Acad Dermatol. 1998 Feb;38(2 Pt 2):318-21. doi: 10.1016/s0190-9622(98)70573-0.
The potential for a variety of local and systemic side effects from the use of potent topical corticosteroids has long been recognized. However, adrenal suppression has only rarely been documented. We describe two patients with profound hypothalamic-pituitary-adrenal axis suppression resulting from the unregulated use of super potent topical corticosteroids.
长期以来,人们一直认识到使用强效外用皮质类固醇可能会产生各种局部和全身副作用。然而,肾上腺抑制的情况却鲜有记录。我们描述了两名因无节制使用超强效外用皮质类固醇而导致严重下丘脑 - 垂体 - 肾上腺轴抑制的患者。